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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIP6
All Species:
32.42
Human Site:
Y430
Identified Species:
59.44
UniProt:
Q15654
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15654
NP_003293.2
476
50288
Y430
R
S
F
H
I
G
C
Y
K
C
E
E
C
G
L
Chimpanzee
Pan troglodytes
XP_001159438
612
65827
Y567
R
D
F
H
V
H
C
Y
R
C
E
D
C
G
G
Rhesus Macaque
Macaca mulatta
XP_001106127
476
50267
Y430
R
S
F
H
I
G
C
Y
K
C
E
E
C
G
L
Dog
Lupus familis
XP_536859
478
50671
Y432
R
S
F
H
I
G
C
Y
K
C
E
E
C
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Y4
480
50915
Y434
R
S
F
H
I
G
C
Y
K
C
E
E
C
G
L
Rat
Rattus norvegicus
Q5XI07
632
68242
Y587
R
D
F
H
V
H
C
Y
R
C
E
D
C
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506023
531
55801
R485
H
C
I
D
D
F
H
R
K
F
A
P
R
C
S
Chicken
Gallus gallus
Q5F464
604
65121
Y559
R
D
F
H
V
Q
C
Y
R
C
E
D
C
G
G
Frog
Xenopus laevis
A5H447
663
70707
P590
D
Y
H
R
R
Y
A
P
R
C
C
V
C
G
D
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
Y595
K
D
Y
H
V
D
C
Y
H
C
E
D
C
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396072
477
52619
Y431
R
S
F
H
I
Q
C
Y
K
C
E
D
C
G
L
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
M368
N
G
R
C
V
A
A
M
G
R
K
F
H
P
E
Sea Urchin
Strong. purpuratus
XP_798292
448
48550
G390
H
P
I
M
P
D
D
G
Q
E
E
T
V
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.1
98.3
89.3
N.A.
86.4
41.7
N.A.
58.5
43.3
30.4
28.7
N.A.
N.A.
36.6
21.4
39.9
Protein Similarity:
100
53.7
98.5
92.2
N.A.
90.2
51.2
N.A.
64.2
53.1
42.6
42.7
N.A.
N.A.
49
35.7
51.6
P-Site Identity:
100
60
100
100
N.A.
100
60
N.A.
6.6
60
20
53.3
N.A.
N.A.
86.6
0
6.6
P-Site Similarity:
100
80
100
100
N.A.
100
80
N.A.
6.6
80
26.6
80
N.A.
N.A.
93.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
16
0
0
0
8
0
0
0
0
% A
% Cys:
0
8
0
8
0
0
70
0
0
77
8
0
77
8
0
% C
% Asp:
8
31
0
8
8
16
8
0
0
0
0
39
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
77
31
0
0
8
% E
% Phe:
0
0
62
0
0
8
0
0
0
8
0
8
0
0
0
% F
% Gly:
0
8
0
0
0
31
0
8
8
0
0
0
0
77
24
% G
% His:
16
0
8
70
0
16
8
0
8
0
0
0
8
0
0
% H
% Ile:
0
0
16
0
39
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
0
0
0
0
0
0
47
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
47
% L
% Met:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
8
0
0
8
0
0
0
8
0
8
0
% P
% Gln:
0
0
0
0
0
16
0
0
8
0
0
0
0
0
0
% Q
% Arg:
62
0
8
8
8
0
0
8
31
8
0
0
8
8
0
% R
% Ser:
0
39
0
0
0
0
0
0
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
0
39
0
0
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
8
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _